For the period 2025–2028, the ETH Domain aims to be internationally competitive and to serve Switzerland by addressing important challenges in the context of education, research and innovation. The ETH Board prioritises five Strategic Areas to respond to most pressing global challenges, and in which the ETH Domain is well positioned to have a strong impact. A set of measures are also identified in the context of the core and key transversal tasks of the Domain, in order to continue achieving excellence in education, research and knowledge and technology transfer. Moreover, the present Strategy addresses the long-term organisational development of the ETH Domain as a whole, aiming at remaining as agile as possible, as well as at strengthening collaboration and exploiting synergies among the institutions of the ETH Domain.